A Pennsylvania nurse who administered lethal or potentially lethal doses of insulin to numerous patients has pleaded guilty to three counts of murder and other charges and been sentenced to life in prison.

A Pennsylvania man who authorities say killed his girlfriend in a Nevada desert has been convicted.

A staffing company that performed COVID-19 contact tracing for Pennsylvania and exposed the private medical information of about 72,000 residents will pay $2.7 million in a settlement with the U.S. Justice Department and a whistleblower.

A decomposed body found in a duffel bag in west Philadelphia have been identified as a 4-year-old boy who authorities say was beaten to death.

A Pennsylvania man says his emotional support alligator named Wally has gone missing amid the coastal marshes of Georgia.

Cannabis could be reclassified for the first time since the Controlled Substances Act became law half a century ago.

Within three or four years, thousands of self-driving tractor-trailers are expected to travel on America’s public freeways.

Authorities have announced new charges against four juveniles arrested following an exchange of gunfire earlier this month between rival groups that wounded three people and sent participants in a joyful celebration of the end of Ramadan in west Philadelphia running for cover.

U.S. police departments have reported a year-over-year increase in sworn officers for the first time since the COVID-19 pandemic and the police killing of George Floyd.

A Pennsylvania school district has reversed the cancellation of an appearance by actor and children’s book author Maulik Pancholy.

Pennsylvania state police say three adults and a pregnant teenager died in a fiery crash as police pursued their vehicle in connection with retail thefts.

Two police officers are on paid leave after the death of an Ohio man who was handcuffed and left facedown on a barroom floor.

Relatives say a 74-year-old woman charged in the armed robbery of a credit union in Ohio last week is a victim of an online scam who may have been trying to solve her financial problems.

Cleveland will pay $4.8 million to the family of a 13-year-old girl was struck and killed by a stolen car during a police pursuit.

A Pennsylvania appeals court has kept alive an Italian heritage group’s challenge to efforts by the city of Pittsburgh to remove a statue of Christopher Columbus from a city park.

A Pennsylvania school district has canceled an upcoming appearance by actor and children’s book author Maulik Pancholy.

The ride-hailing company Uber says it's banned an account that sent a driver to the Ohio home where an 81-year-old man allegedly shot the woman to death.

The Labor Department has issued a new rule intended to protect coal miners from poisonous silica dust that has contributed to the premature deaths of thousands of mine workers from a respiratory ailment known as “black lung” disease.

A stretch of the Ohio River near Pittsburgh remains closed to maritime traffic as crews equipped with sonar look for a barge believed to have sunk over the weekend.

The union that represents a Pittsburgh newspaper’s truck drivers, one of five unions that have been on strike for 18 months, has approved a new contract with the paper’s owners.

Jury selection has started in the retrial of a former corrections officer charged in the death of an inmate at a county jail in northern Ohio.

Worries and frustrations filled Columbiana's Main Street Theatre and Enon Valley's SNPJ Recreation Center Monday as legal experts discussed the East Palestine community's options involving Norfolk Southern's $600 million settlement.

Former President Donald Trump is endorsing U.S. Senate candidate David McCormick of Pennsylvania.

A Pennsylvania state agency has received thousands of applications for the state’s first-ever student-teacher stipends, many times more than the available stipends approved by lawmakers as a way to help end a teacher shortage.

Officials say two major U.S. manufacturers of gun parts have agreed to temporarily halt sales of their products in Philadelphia and elsewhere in Pennsylvania.

Republican lawmakers in Pennsylvania on Wednesday rolled out a counterproposal to Democratic Gov. Josh Shapiro’s plan to boost college enrollment in Pennsylvania.

More than 190,000 women are currently being held in some kind of confinement in the United States — a number that’s been growing rapidly since at least 1980.

We talked to some Valley mental health professionals about DeWine's plans and what they'd like to see happen with them.

President Joe Biden could miss the deadline to be included on the ballot in Ohio this fall.

An independent state-ordered investigation has concluded that Ohio legislative leaders were justified in disciplining a state lawmaker.